News & Stories from the Rogel Cancer Center

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Health Lab

Understanding family history key to early detection of pancreatic cancer

How genetic testing and family history help identify individuals at high risk for pancreatic cancer, enabling earlier screening and better treatment outcomes.
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News Release

How have diagnostic and treatment decisions for prostate cancer changed in recent years?

An analysis of United States data reveals a broad shift away from overtreatment of low-risk prostate cancer. The analysis by University of Michigan Rogel Cancer Center researchers, indicates a shift toward surveillance in response to concerns of overdiagnosis and overtreatment that have hindered screening in the recent past.
Family with mom and dad and three kids sitting on a park bench, dad's arms extended around the family.
Health Lab

Intuition pushed mom to keep checking for breast cancer

Michigan mom had no reason to suspect cancer. But instinct nudged her to find out for sure — and carried her through challenging treatments to remission.
Perforin increases endosomal-mitochondrial contact sites in tumor cells. Left is without perforin; right has perforin.
Health Lab

Immune system protein is a cancer killer on its own, new study shows

New study finds perforin can kill cancer tumor cells even when major granzymes were missing.
Three people stand arm in arm with backs to camera studying a wall of family mementos
Health Lab

Online resources and coaching helped people seek genetic testing for cancer

New study from researchers at the University of Michigan Rogel Cancer Center showed an online resource and phone-based coaching both helped increase rates of genetic testing.
Two U-M faculty headshots with the titling, National Academy of Medicine, presented above their names: Diane Harper and Jacqueline Jeruss.
News Release

Two U-M Researchers Earn Election to National Academy of Medicine

Two U-M Researchers Earn Election to National Academy of Medicine
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Health Lab

Comprehensive DNA sequencing reveals hidden drivers of cancer

Two research papers describe how long-read nanopore sequencing can detect alterations in cancer cells that might be missed by conventional sequencing.
cancer cell blue yellow
Health Lab

‘Molecular glue’ stabilizes protein that inhibits development of non-small cell lung cancer and uterine cancer

University of Michigan researchers found a new protein target PP2A and developed a drug to treat non-small cell lung cancers that have KRAS mutations.
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Health Lab

Exceptional response to immunotherapy gives patient with liver cancer more milestones to celebrate

U-M Health Rogel Cancer Center used single-dose immunotherapy and transplant oncology to treat advanced hepatocellular carcinoma in a 69-year-old patient.
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Health Lab

FDA-approved drug offers hope for patients with polycythemia vera, a rare bone marrow disorder

FDA-approved rusfertide offers new hope for polycythemia vera patients by reducing phlebotomy dependence, easing symptoms, and improving daily life.
little girl with yellow shirt on soccer field smiling ready for soccer
Health Lab

Pediatric patient treated for rare kidney cancer

When 18-month-old Maria was diagnosed with an exceptionally rare kidney cancer, specialists at C.S. Mott Children's Hospital created a customized treatment plan that saved her life.
cells close up blue and green background microscope
Health Lab

Engineered nanoparticles sensitize gliomas to radiotherapy

University of Michigan researchers discovered a new pathway that sensitizes mIDH1 gliomas to radiation in human and mouse mIDH1 glioma cells and mouse models, paving the way for phase 1 clinical trials in humans
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