Pre-implantation Genetic Diagnosis

Pre-implantation Genetic Diagnosis

  • Overview
  • Approach
  • Appointments
  • Locations
  • Doctors
  • Providers

    • What is pre-implantation genetic diagnosis?

    At the University of Michigan Health Center for Reproductive Medicine, we offer a cutting-edge procedure called pre-implantation genetic diagnosis to identify genetic disorders in embryos, and then implant the unaffected embryos using in vitro fertilization. Because of our strong medical genetics program, our center is well situated to offer Pre-implantation genetic diagnosis services to our patients in a timely and efficient manner.

    How are inherited genetic disorders diagnosed?

    Pre-implantation genetic diagnosis is performed when one or both genetic parents have a known genetic abnormality. Testing is performed on an embryo to determine if it also carries the genetic abnormality. This allows us to detect genetic diseases before pregnancy.

    What are the types of inherited genetic disorders?

    This procedure is used to look for DNA-testable disorders with significant morbidities in which quality of life is dramatically affected, including:

    Our Approach

    To determine if you and your partner are candidates for the procedure, you will meet with our genetic counselor to discuss both your case and your options. All the testing performed for in vitro fertilization, including blood tests and ultrasound will be scheduled. You will also require hormone treatment to control your egg production.

    During the process, embryos are created using in vitro fertilization, where eggs and sperm are brought together in a laboratory glass dish to allow the sperm to fertilize an egg. On the third day — when the embryos reach the six- to eight-cell stage — a biopsy is performed to remove one or two cells and determine whether they carry the genetic abnormality. Embryos that are found to not carry the genetic defect are then transferred to the womb. Just over a week later, a pregnancy test will be conducted.

    Pregnancy is not guaranteed and depends on a variety of factors including your age and the number/quality of your embryos.

    Appointment Information

    Schedule an appointment by calling us at 734-763-6295.

    Locations
    • Reproductive Endocrinology Clinic | Briarwood Center for Reproductive Medicine 475 Market Place
      Briarwood Building 1
      Ann Arbor, MI 48108-1649       Get Directions

    Doctors

     Search for a U-M Health doctor     Hanh Nguyen Cottrell, MD

    Hanh Nguyen Cottrell, MD

    Clinical Assistant Professor

    Obstetrics & Gynecology, Reproductive Endocrinology

    James Michael Dupree, IV, MD

    James Michael Dupree, MD

    Clinical Professor

    Urology

    Erica Elizabeth Marsh, MD

    Erica Elizabeth Marsh, MD, MSCI, FACOG

    Professor

    Reproductive Endocrinology, Obstetrics & Gynecology

    Marie Menke, MD

    Marie Menke, MD

    Clinical Associate Professor

    Obstetrics & Gynecology, Reproductive Endocrinology

    Dana Alan Ohl, MD

    Dana Alan Ohl, MD

    Professor

    Urology

    John F Randolph, MD

    Professor

    Reproductive Endocrinology, Obstetrics & Gynecology

    Samantha Beth Schon, MD

    Samantha Beth Schon, MD

    Assistant Professor

    Reproductive Endocrinology, Obstetrics & Gynecology

    Yolanda Smith, MD

    Professor

    Reproductive Endocrinology, Obstetrics & Gynecology

    Natalie Clark Stentz, MD

    Natalie Clark Stentz, MD

    Clinical Assistant Professor

    Reproductive Endocrinology, Obstetrics & Gynecology

    Daphna Stroumsa, MD

    Daphna Stroumsa, MD, MPH

    Assistant Professor

    Obstetrics & Gynecology

    Providers

     Search for a U-M Health provider     Lindsay Renee Brennan, MSW

    Lindsay Renee Brennan, MSW

    Social Worker

    Licensed Clinical Social Worker

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