Congenital Heart Center

We perform more cardiac surgical and open-heart procedures than nearly every other program in the nation.

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Best Children's Hospitals US News & World Report. Ranked in 11 Specialties 2024-25

Michigan's #1 Children's Hospital

C.S. Mott Children's Hospital is honored to be the #1 children’s hospital in Michigan and the only children’s hospital in Michigan to be ranked in all 11 categories for 2024-25.

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Research at the Congenital Heart Center

M-CHORD is our unique research core within the Congenital Heart Center fully dedicated to supporting pediatric and congenital cardiovascular research.  The expertise of our faculty and staff spans the spectrum of clinical investigation including translational research, clinical trials of new drugs and devices, outcomes and health services research, and multicenter collaborative quality improvement. Our investigators are highly productive publishing more than 170 scientific manuscripts each year, supported by more than 50 active research grants.

For more information, please contact Dr. Sara Pasquali or Dr. Caren Goldberg.

We are one of nine centers across the country selected to participate in the Pediatric Heart Network (PHN), funded by the National Heart, Lung, and Blood Institute. Through this network, our patients have access to clinical trials of cutting-edge therapies and interventions.

The PHN Single Ventricle Reconstruction Trial, led by U-M Congenital Heart Center investigators, was the first multi-center congenital heart surgery randomized trial ever accomplished. U-M Congenital Heart Center investigators also lead the PHN biorepository, PHN Integrated CARdiac Data and Outcomes (iCARD) Collaborative, and numerous other PHN efforts.

We lead the development and testing of novel devices and treatments tailored toward the pediatric heart population. 

Examples include:

3-D airway splints: As reported in the New England Journal of Medicine, we have developed and implanted the first bioresorbable airway splints created using 3-D printing technology. These splints have been implanted in more than 25 patients to date to treat life-threatening airway narrowing, many of whom are impacted by congenital heart disease.

3D Visualization Technologies: Our heart center is developing unique ways of using virtual and printed 3D models to prepare for and even guide cardiac surgery and transcatheter interventions.  We have also teamed up with other U-M experts to advance the use of computational fluid dynamics to help predict procedural outcomes in our patients.

Donor heart preservation technology: Our investigators are developing technology to allow prolonged perfusion of donor hearts( with the aim of improving organ availability and viability for heart pediatric transplant.

Regenerative medicine: Our team is leading studies exploring new treatments for children with heart failure through the use of stem cells and tissue engineering.

We lead data coordinating center activities for Cardiac Networks United, which integrates several large networks spanning in total more than two-thirds of the nation’s congenital heart programs. These initiatives bring multiple data sources and expertise together to drive novel research otherwise not possible, and translate discovery to the bedside across hospitals to improve outcomes.

Our investigators lead national efforts geared toward understanding quality of congenital heart care, investigating variation in quality and costs of care across centers, and designing initiatives to reduce this variation and improve care and outcomes.

Through multiple lines of investigation, we aim to study and develop more individualized strategies for prevention, recognition, and treatment of adverse events tailored to the specific traits and needs of each heart patient. 

We are one of the first programs in the country to systematically track long-term survival, morbidities, and quality of life for children undergoing heart surgery at our center, regardless of where they live or receive follow-up care. We have developed a novel “patient-reported outcomes” portal that will drive a better understanding of these critical outcomes, conduct numerous studies geared toward optimizing neurodevelopment, and have recently initiated a new program focused on expanding psychosocial care and research.

News & Stories

baby on blanket saying little blessing
Health Lab

Specialized local care gives baby with severe heart condition a stronger start before surgery

Newborn with a complex congenital heart defect receives coordinated, specialty care close to home while gaining strength before surgery.
Health Lab

How to use an AED in a cardiac emergency

A step-by-step guide on how to use an automated external defibrillator, or AED in a cardiac arrest or emergency
girl with short blonde hair holding a sign that says she matched to michigan residency
Health Lab

Fontan patient inspires as pediatric cardiology fellow

A pediatric cardiology fellow at Michigan shares her experience being a doctor taking care of children who have the same, or similar, heart issues like she did as a child.
Health Lab

How lifesaving care after teen’s sudden cardiac arrest made motherhood possible years later

Once revived after a sudden cardiac arrest at soccer practice as a teenager, a woman returns to the same care team more than a decade later to safely grow her family.
Paisley, a young girl with long brown hair that is pulled back on top, is wearing oversized heart-shaped red sunglasses and a blue Save A Heart t-shirt with yellow hearts across the top. She is standing with her arms extended upwards in a gesture of victory in front of a block M.
Philanthropy News

Small But Mighty: Paisley’s Brave Journey Inspires Support for Children’s Heart Care

Your gift to the Save A Heart Campaign at C.S. Mott Children's Hospital fuels lifesaving breakthroughs for kids like Paisley who are living with heart defects.
heart beating in young child drawn in blue with red heart and pink brain
Health Lab

Study to focus on factors influencing brain development in kids with congenital heart disease

Researchers examine how early heart procedures may influence neurodevelopment in babies with limited blood flow to the lungs.