More articles about: Diabetes

Abnormal changes in protein levels and patterns can result in diseases. Understanding protein organization can improve treatments and minimize disease symptoms. A team of researchers developed a new technology called pathology-oriented multiplexing, or PathoPlex, to map more than 140 different proteins across 40 tissue samples.

In the U.S., dietary obesity has a prevalence of 40% and obesity increases the risk of other chronic diseases such as heart disease and diabetes. Even though anorexia nervosa has a prevalence of 1%, it is the second-highest death rate of any mental illness. Roger Cone discusses how melanocortin receptors can be used to treat both obesity and anorexia.

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding. In a new study, researchers at the University of Michigan found that mitochondria also accumulate misfolded proteins, which kills insulin-producing β-cells of patients with type 2 diabetes.

A simple ultrasound of a patient’s thigh or shoulder muscle may detect insulin resistance before it progresses to type 2 diabetes or even prediabetes. In a study, Michigan Medicine researchers performed muscle ultrasounds on 25 patients who were also evaluated for insulin resistance.

University of Michigan researchers show that using continuous glucose monitors can help measure glucose accurately during DKA and potentially prevent ICUs from being overwhelmed.

People with diabetes often have a host of other conditions including cardiovascular disease and kidney disease driven by inflammation. On today's episode, we talk with Dr. Katherine Gallagher, professor of surgery, professor of microbiology and immunology, and the Leland Ira Doan Research Professor of Vascular Surgery at U of M, who is looking at how epigenetics - the influence of environmental factors and behaviors impact on gene expression - might explain changes in the immune system in people with cardiovascular disease, diabetes, and other conditions related to inflammation.

Diabetic retinal disease screening remains challenging because patients often do not have any symptoms in the early stages and, therefore, misunderstand the importance of regular screenings. In a recent publication Thomas Gardner discusses current screening recommendations and treatment options for DRD.

Today on The Fundamentals, we have a conversation with Dr. Sonya Wolf-Fortune, Assistant Professor of Pharmacology, whose work focuses on investigating the underlying mechanisms of psoriasis, diabetes, and other inflammatory conditions. Dr. Wolf-Fortune is trying to uncover what sets off the cascades of inflammation related to these conditions and related diseases.

Women diagnosed with chronic conditions, such as osteoarthritis, multiple sclerosis and diabetes, experiencing poor sleep are at a higher risk of needing mobility aids sooner in life. Addressing sleep issues in these women may be crucial to better mobility.

Mitochondria are essential for generating energy that fuels cells and helps them function. In a new study researchers used mice to show that dysfunctional mitochondria also trigger a response that affects the maturation and function of β-cells.

For people with erectile dysfunction, penile prosthesis surgery provides a safer, and more successful treatment option, than you might think.

The National Diabetes Prevention Program was created by the Centers for Disease Control and Prevention in 2010 to offer an effective way to help prevent type 2 diabetes. U-M researchers evaluated the uptake and outcomes of the National DPP and found that enrollees saved in medical costs and had a reduced risk of developing type 2 diabetes.

Kim Hartman is an artist with Type 1 diabetes. She started developing vision problems and doctors at Michigan Medicine helped her slow the vision loss and manage it.

A low calorie diet and high intensity exercise can reduce nerve damage in prediabetic mice, according to a Michigan Medicine study.

Research highlights alarming rates of diabetic retinopathy; an ophthalmologist shares what to know.