My primary research interests are twofold: 1) To translate basic science findings from animal models to human application in kidney transplantation. 2) Outcomes research in the area of kidney transplantation with a focus on recipient and donor obesity, variation in practice patterns and understanding the clinical impact and economic implications of various post kidney transplant complications.
My current work focuses on understanding changes in glomerular and podocyte parameters early after kidney transplantation and their impact on long term allograft survival. Using a multidimensional approach that involves a combination of clinical, glomerular morphometric, histological and transcriptomic data we are in the process of defining individuals at high risk for post-transplant glomerular disease and obtain mechanistic insights into disease causation and progression. My work is currently funded via intramural grants from the Michigan Nutrition and Obesity Research Center as well as the George O’Brien Kidney Center.
Besides my clinical and research interests, I serve as faculty at the UM-KECC (Kidney Epidemiology and Cost Center) where our multidisciplinary team is working to develop quality metrics for dialysis facilities designed to improve access to kidney transplantation.