Gregory Adam Clines, MD, PhD

Dr. Gregory Clines is an Associate Professor of Internal Medicine and the Chief of the Division of Metabolism, Endocrinology & Diabetes (MEND) at the University of Michigan. He received his MD and PhD degrees at the University of Texas Southwestern Medical Center at Dallas. He then completed internal medicine training at Duke University and an endocrinology fellowship at the University of Virginia. Before joining the University of Michigan in 2013, he was on the faculty at the University of Virginia and the University of Alabama at Birmingham.

Dr. Clines has been studying and thinking about bone diseases for nearly 30 years. His basic science laboratory studies how novel factors such as hypoxia, androgens, endothelins, Wnt signaling, and other factors regulate the osteoblast-cancer cell synergy in bone metastasis. His other research interests include understanding how sex steroids regulate skeletal size and shape, and the development of novel imaging techniques to assess bone quality.

His clinical interests include metabolic and genetic bone diseases as well as general endocrinology. Dr. Clines sees patients at the Metabolism, Endocrinology & Diabetes Clinic (Metabolic Bone Disease Clinic) and at the Ann Arbor Veterans Affairs Medical Center.

Disorders of bone and mineral metabolism

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Molecular mechanisms of breast and prostate cancer bone metastasis