Andrea Tara Obi, MD

University of Michigan Health participates with most health insurance plans.

Dr. Obi has a long-standing interest in disorders of thrombosis. Her laboratory focuses on defining the role of the immune system in acute deep venous thrombosis (DVT) and sequelae. The long term goal is to uncover mechanisms responsible for idiopathic and sepsis related DVT and identify new targets for therapeutic intervention. The widespread use of anticoagulants is risky and unsuccessful in completely preventing DVT and downstream effects such as post thrombotic syndrome (PTS). Since her arrival at the University of Michigan, she has focused efforts in both the laboratory setting utilizing various mouse models of DVT under different conditions such as pneumonia and sepsis to characterize thrombogenesis and the post thrombotic response on a cellular and molecular level. Importantly, this work was carried out in conjunction with clinical studies to ensure bench to bedside translation. The ultimate goal is to translate a better understanding of the intersection of innate immunity and thrombosis to new pharmacologic targets and treatment modalities.

https://www.ncbi.nlm.nih.gov/myncbi/1PwP4krs6xrcFo/bibliography/public/