Jason Scott Knight, MD
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About
Dr. Knight received his M.D. and Ph.D. degrees from the University of Michigan and completed his molecular biology Ph.D. research in the laboratory of Dr. Erle Robertson at the University of Pennsylvania. His fellowship in rheumatology was at the University of Michigan, where he pursued postdoctoral research in the laboratory of Dr. Mariana Kaplan. During fellowship, he received the prestigious American College of Rheumatology Distinguished Fellow Award, as well as a Rheumatology Research Foundation Scientist Development Award.
As a faculty member, he has been awarded the Jerome W. Conn Award for Excellence in Research by the Department of Internal Medicine. He has also received the Edmund L. Dubois Award for young lupus researchers from the American College of Rheumatology and the Mary Betty Stevens Young Investigator Prize from the Lupus Foundation of America. He is a member of the American Society for Clinical Investigation.
His NIH-funded research laboratory has also received financial support from the Burroughs Wellcome Fund, Department of Defense, Lupus Research Alliance, and Rheumatology Research Foundation, His research group is working to better understand the triggers and effectors of autoimmunity in lupus and the related antiphospholipid syndrome (APS). His group is also interested in other diseases characterized by excessive neutrophil-mediated inflammation including diabetes and COVID-19.
Dr. Knight is an international leader in the clinical care of APS patients and the role of inflammation in APS. Contact Dr. Knight if you are interested in participating in APS research studies.
Areas of Practice
Systemic Lupus Erythematosus, Antiphospholipid Syndrome
Expertise
Locations
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Rheumatology Clinic | Taubman Center 1500 E Medical Center Dr
Floor 3 Reception A
Ann Arbor, MI 48109-5358Get Directions
Insurance Accepted
University of Michigan Health participates with most health insurance plans.
Education & Training
Medical School or Training
Residency
Fellowships
Board Certifications
Professional Organizations
Research Overview
Interplay between the immune system and thrombosis.
Role of neutrophils and neutrophil extracellular traps (NETs) in autoimmune disease.
Interaction of neutrophils and endothelial cells in antiphospholipid syndrome (APS).
Extracellular purine species as regulators of inflammation in systemic lupus erythematosus (SLE).
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Patient Ratings & Comments
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Patient Ratings
120 Patient Ratings
Patient Comments
June 19, 2026 - "Dr. Knight is simply the best! Very easy to talk to, knowledgeable and gives a lot of insight."
June 14, 2026 - "Dr. Knight is a very good caring Dr."
June 5, 2026 - "Dr Knight is the best doctor I have ever seen. He is extremely knowledgeable, knows how to talk to patients, and is proactive in his care. His research is so important to so many!"
May 20, 2026 - "Dr. Knight was absolutely fantastic and has been a life changing experience for us. [...] Dr. Knight was such a breath of fresh air. His knowledge, extensive experience, and ability to problem solve by analyzing the "big picture" were everything we had hoped for and beyond. We are so impressed with Dr. Knight and he truly is a great asset to UofM."
April 30, 2026 - "Dr. Knight is always patient and listens to every word and asks questions and never makes me feel rushed"
April 18, 2026 - "Dr. Knight takes the time to listen to me and truly shows a concern for my health. He discusses my treatment options and includes me in decisions about my care."
April 3, 2026 - "It seemed like Dr Knight really wanted to help me"
March 13, 2026 - "Dr. Knight is a stellar doctor. He listens and shows genuine concern. I am fortunate to have him as my Rheumatoligst"
March 11, 2026 - "Complete faith in Dr Knight"
March 6, 2026 - "Dr. Knight was very patient, explained things thoroughly and looked at the whole picture."
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