More articles about: Drug Discovery
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Leukemia drug secures FDA approval
Komzifti (ziftomenib), developed at Michigan Medicine, has been approved for patients with acute myeloid leukemia caused by the NPM1 gene mutation.
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Biologic drug reduces symptoms, hospitalization for severe pulmonary hypertension after diagnosis
Prescribing the biologic drug sotatercept alongside standard treatment for the most severe form of pulmonary hypertension significantly reduces the likelihood of worsening disease when added within the first year after diagnosis, according to a study published in the New England Journal of Medicine by Michigan Medicine.
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Drug candidate successfully treats atherosclerosis, fatty liver disease in large mammals
A compound that was previously found to treat severe fatty liver disease also reduces atherosclerosis, a primary driver of cardiovascular death, in non-human primates. The drug candidate was developed at the University of Michigan.
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An ultrasound-activated hydrogel for steady, sustained drug delivery
Researchers have developed a new composite hydrogel capable of achieving sustained, zero-order drug release using ultrasound as a trigger.
Health Lab
Tiny model organs detect liver toxicity of new drugs
A University of Michigan-led study provided evidence of the efficacy of a new drug-induced liver injury screening platform using human liver organoids, or tiny 3D models of organs developed from patients’ stem cells that grow in petri dishes.
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Potential drug treats fatty liver disease in animal models, brings hope for first human treatment
For nonalcoholic steatohepatitis, also known as NASH, a potential drug may treat the fatty liver disease in animal models researchers find.
