Gregory Adam Clines, MD, PhD
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About
Dr. Gregory Clines is an Associate Professor of Internal Medicine in the Division of Metabolism, Endocrinology & Diabetes (MEND) at the University of Michigan. He received his MD and PhD degrees at the University of Texas Southwestern Medical Center at Dallas. He then completed internal medicine training at Duke University and an endocrinology fellowship at the University of Virginia. Before joining the University of Michigan in 2013, he was on the faculty at the University of Virginia and the University of Alabama at Birmingham.
Dr. Clines has been studying and thinking about bone diseases for nearly 30 years. His basic science laboratory studies how novel factors such as hypoxia, androgens, endothelins, Wnt signaling, and other factors regulate the osteoblast-cancer cell synergy in bone metastasis. His other research interests include understanding how sex steroids regulate skeletal size and shape, and the development of novel imaging techniques to assess bone quality.
His clinical interests include metabolic and genetic bone diseases as well as general endocrinology. Dr. Clines sees patients at the Metabolism, Endocrinology & Diabetes Clinic (Metabolic Bone Disease Clinic) and at the Ann Arbor Veterans Affairs Medical Center.
Areas of Practice
Disorders of bone and mineral metabolism
Expertise
Locations
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Metabolism, Endocrinology & Diabetes Clinic | Domino's Farms 24 Frank Lloyd Wright Dr Ste 1300
Lobby C
Ann Arbor, MI 48105-9484Get Directions -
Pediatric Orthopaedic Surgery Clinic | C. S. Mott Children's Hospital 1540 E Hospital Dr
Floor 3 Reception C
Ann Arbor, MI 48109-4213Get Directions
Insurance Accepted
University of Michigan Health participates with most health insurance plans.
Education & Training
Medical School or Training
Residency
Fellowships
Board Certifications
Professional Organizations
Research Overview
Molecular mechanisms of breast and prostate cancer bone metastasis
Links
Patient Ratings & Comments
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Patient Ratings
68 Patient Ratings
Patient Comments
October 16, 2025 - "Dr. Clines is an outstanding doctor. He is very thorough and pleasant to respond to all questions asked."
July 16, 2025 - "Dr. Clines is great - listens, explains, knowledgeable"
April 23, 2025 - "I am very fortunate to have Dr. Clines as my physician. His exceptional knowledge and vast medical experience is a great asset to have by my side!"
April 10, 2025 - "I honestly do not have anything bad to say. Dr. Clines was nice and courteous. He took time to listen and understand what I had to say, which was nice. He also took the time to answer any questions I had and put them in a way I understood."