Phosphate in Blood Test
A phosphate test measures the amount of phosphate in a blood sample. Phosphate is a charged particle (ion) that contains the mineral phosphorus. The body needs phosphorus to build and repair bones and teeth, help nerves function, and make muscles contract. Most (about 85%) of the phosphorus contained in phosphate is found in bones. The rest of it is stored in tissues throughout the body.
The kidneys help control the amount of phosphate in the blood. Extra phosphate is filtered by the kidneys and passes out of the body in the urine. A high level of phosphate in the blood is usually caused by a kidney problem.
The amount of phosphate in the blood affects the level of calcium in the blood. Calcium and phosphate in the body react in opposite ways: as blood calcium levels rise, phosphate levels fall. A hormone called parathyroid hormone (PTH) regulates the levels of calcium and phosphorus in your blood. When the phosphorus level is measured, a vitamin D level, and sometimes a PTH level, is measured at the same time. Vitamin D is needed for your body to take in phosphate.
The relation between calcium and phosphate may be disrupted by some diseases or infections. For this reason, phosphate and calcium levels are usually measured at the same time.
Why It Is Done
This test may be done to check phosphate levels if you have kidney disease or bone disease. It helps find problems with certain glands, such as the parathyroid glands. The test is also used to find a cause for abnormal vitamin D levels.
How To Prepare
Tell your doctor ALL the medicines, vitamins, supplements, and herbal remedies you take. Some may affect the test results. Your doctor will tell you if you should stop taking any of them before the test and how soon to do it.
How It Is Done
A health professional uses a needle to take a blood sample, usually from the arm.
A heel stick is used to get a blood sample from a baby. The baby's heel is poked, and several drops of blood are collected. A baby may have a tiny bruise where the heel was poked
How long the test takes
This test will take a few minutes.
How It Feels
When a blood sample is taken, you may feel nothing at all from the needle. Or you might feel a quick sting or pinch.
A brief pain, like a sting or a pinch, is usually felt when the lancet punctures the skin. A baby may feel a little discomfort with the skin puncture.
There is very little chance of having a problem from this test. When a blood sample is taken, a small bruise may form at the site.
There is very little risk of a problem from a heel stick. A baby may get a small bruise at the puncture site.
Phosphate levels are usually higher in children than in adults. That's because of the active bone growth occurring in children.
Results are usually available in 1 to 2 hours.
Each lab has a different range for what's normal. Your lab report should show the range that your lab uses for each test. The normal range is just a guide. Your doctor will also look at your results based on your age, health, and other factors. A value that isn't in the normal range may still be normal for you.
High phosphate levels may be caused by:
- Some tumors such as lymphoma.
- Kidney disease, underactive parathyroid glands (hypoparathyroidism), acromegaly, healing fractures, untreated diabetic ketoacidosis, or certain bone diseases.
- Too much vitamin D in the body.
Low phosphate levels may be caused by:
- Hyperparathyroidism, certain bone diseases (such as osteomalacia), lack of vitamin D, or some kidney or liver diseases.
- Severe malnutrition or starvation.
- A condition such as sprue that prevents the intestines from absorbing nutrients properly.
- Alcohol use disorder.
- High calcium levels.
- Some types of tumors.
Current as of: April 13, 2022
Author: Healthwise Staff
Medical Review:E. Gregory Thompson MD - Internal Medicine & Kathleen Romito MD - Family Medicine & Alan C. Dalkin MD - Endocrinology