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3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
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Animal studies suggest that fucoxanthin, an antioxidant found naturally in some types of seaweed, might prevent the growth of fat tissue and reduce abdominal fat.
Fucoxanthin is a member of the carotenoid family, and is found naturally in some types of seaweed, such as wakame. Animal studies by one group of researchers suggest that fucoxanthin might prevent the growth of fat tissue and reduce abdominal fat. However, no studies have been done to see if this effect is achievable in humans, and one study found that fucoxanthin present in seaweed was absorbed quite poorly from the human digestive tract. Human research is needed to understand the value, if any, of fucoxanthin for helping with weight loss.
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1. Yan X, Chuda Y, Suzuki M, Nagata T. Fucoxanthin as the major antioxidant in Hijikia fusiformis, a common edible seaweed. Biosci Biotechnol Biochem 1999;63:605-7.
2. Sachindra NM, Sato E, Maeda H, et al. Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin and its metabolites. J Agric Food Chem 2007;55:8516-22.
3. Maeda H, Hosokawa M, Sashima T, et al. Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin. J Oleo Sci 2007;56:615-21.
4. Maeda H, Hosokawa M, Sashima T, Miyashita K. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice. J Agric Food Chem 2007;55:7701-6.
5. Maeda H, Hosokawa M, Sashima T, et al. Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Biochem Biophys Res Commun 2005;332:392-7.
6. Yoshiko S, Hoyoku N. Fucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells. In Vivo 2007;21:305-9.
7. Sugawara T, Matsubara K, Akagi R, et al. Antiangiogenic activity of brown algae fucoxanthin and its deacetylated product, fucoxanthinol. J Agric Food Chem 2006;54:9805-10.
8. Nishino H, Murakosh M, Ii T, et al. Carotenoids in cancer chemoprevention. Cancer Metastasis Rev 2002;21:257-64 [review].
9. Shiratori K, Ohgami K, Ilieva I, et al. Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Exp Eye Res 2005;81:422-8.
10. Asai A, Yonekura L, Nagao A. Low bioavailability of dietary epoxyxanthophylls in humans. Br J Nutr 2008 Jan 11;:1-5 [Epub ahead of print].
Last Review: 03-24-2015
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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2018.
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