Acyclovir Buccal Tablet (ACYCLOVIR TABLET - BUCCAL)


Do not chew or swallow it whole.

Peel back foil, carefully remove tablet using dry hands. Do not push the tablet through the foil.

Use the medicine as soon as you first notice symptoms of a cold sore, such as itching, burning or tingling. It is best to use before the cold sore appears.

The tablet needs to be inserted into the gum pocket area in front of the upper teeth. Place the round side of the tablet to the upper gum, above the tooth to the left or right of the center two teeth, on the same side of the mouth where the cold sore is starting. Leave the tablet in place, and gently press your finger on the outside of your upper lip for 30 seconds to help the tablet stick to your gum.

The tablet will dissolve slowly over several hours. You may eat and drink with the tablet in place, but do not brush your teeth, chew gum, or wear an upper denture until the tablet dissolves. You may gently rinse with water.

If the tablet comes off within 6 hours, reapply the same tablet right away. If it will not stay in place, apply a new tablet. If you accidentally swallow the tablet within 6 hours, drink a glass of water and apply a new tablet. If you swallow the tablet or it falls off after 6 hours, you do not need to reapply it or use a new one.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Tell your doctor and pharmacist about all your medicines. Include prescription and over-the-counter medicines, vitamins, and herbal medicines.

Tell your doctor if symptoms do not get better or if they get worse.

Do not take the medicine more than once during 24 hours.

Brand Name(s): Sitavig

Generic Name: Acyclovir


Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Speak with your health care provider before receiving any vaccinations.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • headaches
  • irritation of mouth and gum tissue

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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