Christina Vadala Angeles, MD
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About
Dr. Angeles is an Associate Professor with Tenure of Surgery, Associate Professor of Dermatology, and Faculty Member in the Cancer Biology PhD Program at the University of Michigan in the Division of Surgical Oncology. She earned her medical degree at Tufts University School of Medicine. She completed general surgery residency at New York Presbyterian-Weill Cornell Medical Center. While in residency she completed a two-year basic/translational science Surgical Oncology Research Fellowship at Memorial Sloan-Kettering Cancer Center (MSKCC) focusing on the molecular biology and novel therapeutics for sarcoma. After residency, Dr. Angeles returned to MSKCC and completed a clinical Complex Surgical Oncology Fellowship. Dr. Angeles is board-certified in both General Surgery and Complex General Surgical Oncology. She is the Director of the Regional Cancer Therapies Clinic at University of Michigan/Rogel Cancer Center.
Dr. Angeles is a nationally recognized surgeon-scientist dedicated to advancing cancer care through innovative research and compassionate patient care. As the lead investigator for multiple clinical trials at the Rogel Cancer Center, she is at the forefront of developing new treatments for melanoma and sarcoma. Her laboratory studies the immune system’s role in fighting cancer, with a special focus on how resident memory T cells can help create long-lasting protection against tumors. By combining basic science and translational research, Dr. Angeles and her team are working to transform discoveries in the lab into effective new therapies for patients. Dr. Angeles’s research has been supported by the American Cancer Society, the Melanoma Research Alliance, the Society of Surgical Oncology, and the National Institutes of Health’s National Cancer Institute (NCI-NIH).
Committed to excellence in both science and patient care, Dr. Angeles is a Fellow of the American College of Surgeons, a Fellow of the Society of Surgical Oncology, and an active member of professional societies including the American Society of Clinical Oncology (ASCO), the Society of Surgical Oncology (SSO), the Connective Tissue Oncology Society (CTOS), and the Society for Immunotherapy of Cancer (SITC). She also serves as Chair of the Society of Surgical Oncology's Research Committee, helping to shape the future of cancer research and treatment.
Clinical Specialization:
Dr. Angeles is a board-certified surgical oncologist whose clinical practice focuses on patients with soft tissue cancers including sarcoma, melanoma, and non-melanoma cutaneous malignancies. Dr. Angeles cares for patients in a robust multidisciplinary fashion and provides education and counseling to her patients in order to allow shared decision making for the surgical management of their disease.
Areas of Practice
Sarcoma, Melanoma and Non-Melanoma Skin Cancers, Gastrointestinal Stromal Tumor (GIST), Complex GI Malignancies
Expertise
Locations
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Surgical Oncology Clinic | Rogel Cancer Center 1500 E Medical Center Dr
Floor 1
Ann Arbor, MI 48109-5916Get Directions
Insurance Accepted
University of Michigan Health participates with most health insurance plans.
Education & Training
Medical School or Training
Residency
Fellowships
Board Certifications
Research Overview
Dr. Angeles’ translational research efforts are focused on the mechanism and effects of immunotherapy, specifically investigating the role of resident memory T cells in providing durable cancer immunity.
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Patient Ratings & Comments
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Patient Ratings
105 Patient Ratings
Patient Comments
October 30, 2025 - "Dr. Angeles is very knowledgeable and through, she clearly explains results and procedures answering all of our questions puts us at ease."
September 23, 2025 - "Dr. Angeles is the best! She is always patient with all the questions I asked her and answers each one thoroughly for me. She is kind, informative, and professional and helped me go through the different decisions and scenarios for my treatments."
August 21, 2025 - "Dr. Angeles was everything I would want in a Physician. We need more like her. Her care for my situation was excellent, as was her professionalism."
June 26, 2025 - "I am strongly compelled to share my experience with Dr. Christina Angeles. In addition to the deep understanding of my condition and the necessary and complicated surgery required to rectify it, Dr. Christina demonstrated an innate ability to reach the emotional/human side of the situation, and to embrace and treat it like no other. (The force is strong with this one) The comfort level and confidence both my Fiance [...] and I felt after our consultations with Dr Christina will be remembered for the rest of our lives and we will remain very grateful for it. Wishing Dr. Christina much success!"
April 15, 2025 - "Doctor Angeles is the most amazing surgeon and person I have ever met! From day 1 she was positive, informational, and willing to give me all of her time I may have needed to understand my situation. She laid out a plan of attack with approximate days along the way that procedures and things would most likely happen and everything she said was spot on. She performed a flawless surgery and removed all of my cancer. She will forever be my angel."
February 8, 2025 - "Dr. Angeles was very nice and knowledgeable. She is awesome. She gave me a hug before she left. U of M is very lucky to have her."
December 17, 2024 - "Dr. Angeles and [...] were so kind, gentle and understanding."
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