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  3. News: 000 All Research News + High blood pressure and hypertension + Type 2 + Nutrition

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Foley catheter
May 05, 2015

Who benefits from a catheter – and who doesn't? New guide for hospital teams aims to protect patients from UTI

What’s the only thing worse than having a urinary catheter when you’re in the hospital?  Having one and getting a urinary tract infection (UTI) – or worse – as a result. Now, a new detailed guide gives doctors and nurses information to help decide which hospital patients may benefit from a urinary catheter – and which ones don’t.

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Fuzzy brain
May 04, 2015

“Fuzzy thinking” in depression & bipolar disorder: New research finds effect is real

People with depression or bipolar disorder often feel their thinking ability has gotten “fuzzy”, or less sharp than before their symptoms began. Now, researchers have shown in a very large study that effect is indeed real – and rooted in brain activity differences that show up on advanced brain scans.

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Lycera logo
May 01, 2015

“Made in Michigan” times three: First clinical trials begin for drug developed at U-M and licensed to a U-M spinoff based on campus

For any biotechnology company, getting the first product out of the lab and into patients in a clinical trial is a major milestone, and a cause for celebration. But not many of those companies get to celebrate on the campus where the idea for their product was born and first developed.

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C. difficile bacteria cell
April 24, 2015

Are hospitals doing all they can to prevent C. diff infections? Not yet, new study suggests

Nearly half of American hospitals aren’t taking key steps to prevent a kind of gut infection that kills nearly 30,000 people annually and sickens hundreds of thousands more – despite strong evidence that such steps work, according to a new study.

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Kellogg Eye Center
April 23, 2015

Rare Mutation Causes Vitamin A Deficiency and Eye Deformities

New research helps explain genetic basis for congenital eye malformations, including small eyes, poor vision, and the complete absence of eyes.

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April 20, 2015

Hospital costs lower in Michigan than in Indiana, Wisconsin; Michigan’s certificate of need laws, dominant insurer likely contributed to differences

A new report shows substantial variation in hospital costs between Indiana, Michigan and Wisconsin, with Michigan as the lowest cost among the three states.

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CPR
April 17, 2015

Should they stay or should they go? Study finds no harm from hospital policies that let families observe CPR

When a hospital patient’s heart stops, the drama starts, as doctors and nurses work furiously at resuscitation. Some hospitals allow family members to watch, while the majority do not. Now, a study has shown for the first time on a national scale that patients do just as well after a cardiac arrest either way.

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HIO spheres
April 16, 2015

To fight nasty digestive bugs, U-M scientists set out to build a better gut – using stem cells

If you got hit with any of the ‘intestinal bugs’ that went around this winter, you’ve felt the effects of infectious microbes on your digestive system. But scientists don’t fully understand what’s going on in gut infections like that. Now, a new $6.4 million grant will fuel research based on stem cells to find out.

April 13, 2015

Network “hubs” in the brain attract information, much like airport system

"Hubs" in the brain -- highly connected regions that like hubs of the airport system -- act as critical destinations where information is received and integrated.

April 06, 2015

Obgyn training in Sub-Saharan Africa bolstered by new collections shared both online and offline

New project provides free access to educational materials to support ob-gyn training in Africa and improve maternal, newborn care. 

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Teens with guns
April 06, 2015

Young guns: U-M study finds high rate of firearm violence in high-risk youth after assault injury

Two young men in their late teens sit in adjacent rooms of an inner-city emergency room. One is getting care for injuries he suffered in a fight, the other, for a sore throat. A study finds that the one who had been in a fight will have a nearly 60 percent chance of becoming involved in a violent incident involving a firearm within the next two years.

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Heart EKG
April 06, 2015

Study: Near-death brain signaling accelerates demise of the heart

What happens in the moments just before death is widely believed to be a slowdown of the body’s systems as the heart stops beating and blood flow ends. But there's a brainstorm happening, strongly synchronized with heart rhythm. Blocking this brain outflow may change the odds of survival for those who suffer cardiac arrest. 

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Boosting brain cells' appetites
April 02, 2015

The brain-belly connection: Scientists find key genetic triggers in weight-regulating brain cells

The little voice inside your head that tells you to eat, or stop eating, isn’t a little voice – it’s actually a cluster of about 10,000 specialized brain cells. And now, an international team of scientists has found tiny triggers inside those cells that give rise to this “voice”, and keep it speaking throughout life.

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Illustration of brain with dollar sign
April 01, 2015

Study: Neurologists’ Focus on Face-to-Face Time with Patients Undervalued by Medicare

Most neurologists provide face-to-face care of neurology patients, many of whom require extensive evaluation and management. However, a new study finds face-to-face care by neurologists is severely undervalued by Medicare and reimbursed at a substantially lower rate than what Medicare pays doctors for performing tests and procedures.

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Healthy Michigan Plan logo
March 31, 2015

On first anniversary of Michigan's Medicaid expansion, U-M researchers examine its impact

One year ago, the first Michiganders gained health insurance coverage under the Healthy Michigan Plan, a unique form of Medicaid expansion tailored to the state’s residents. Now, more than 603,000 people have coverage under the plan -- and U-M researchers are hard at work to study how the new coverage affected them, their health care providers, and the state as a whole.

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Jolanta Grembecka and Dmitry Borkin examine the compound they created
March 30, 2015

Researchers develop new potential drug for rare leukemia

Researchers at the University of Michigan Comprehensive Cancer Center have developed a new drug candidate that shows potential in laboratory studies against a rare type of acute leukemia. And additional studies suggest the same compound could play a role in prostate cancer treatment as well.

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ECMO diagram
March 25, 2015

Experience saves lives: Study of advanced life-support reveals big differences in adult survival rates

An advanced form of life support that takes over for the failing hearts and lungs of critically ill patients saves lives. But for adults, the odds of surviving depend on which hospital provides the life-supporting treatment – with the best odds at ones that use the technique dozens of times a year, a new study finds.

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lung organoid viewed under a microscope
March 23, 2015

Scientists coax stem cells to form 3-D mini lungs

The advantage of growing the 3D structure of lung tissue is that their organization bears greater similarity to the human lung, making them a potential tool for research.

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PICC
March 20, 2015

Serious risks from common IV devices mean doctors should choose carefully, U-M experts say

Every day, patients around the country get IV devices placed in their arms, to make it easier to receive medicines or have blood drawn over the course of days or weeks. But these PICC lines, as they’re called, also raise the risk of potentially dangerous blood clots. Now, a U-M team has shown how serious that clot risk really is for hospitalized patients, and what factors put patients at highest risk.

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Teenagers Driving Cars
March 19, 2015

Thinking of drinking and driving? What if your car won’t let you?

If every new car made in the United States had a built-in blood alcohol level tester that prevented impaired drivers from driving the vehicle, how many lives could be saved, injuries prevented, and injury-related dollars left unspent? Researchers at the University of Michigan Injury Center and the University of Michigan Transportation Research Institute studied the impact of installing these alcohol ignition interlock devices in all newly purchased vehicles over a 15-year period; their estimates of injury prevention and cost savings are significant.

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Gary Hammer
March 18, 2015

Study suggests precision medicine for adrenal cancer

In a randomized phase 3 trial, adrenal cancer patients receiving the investigational drug linsitinib fared no better than patients receiving a placebo. But the researchers noticed a small subset of patients who had significant response and remained on the drug for an extended time.

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Brain
March 18, 2015

Are antipsychotic drugs more dangerous to dementia patients than we think?

Drugs aimed at quelling the behavior problems of dementia patients may also hasten their deaths more than previously realized, a new U-M study finds.

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naproxen pills
March 11, 2015

Naproxen plus acid blocking drug shows promise in preventing bladder cancer

Researchers used the proton pump inhibitor omeprazole, a commonly used acid inhibitor, in combination with naproxen and found it was effective at preventing bladder cancer in an animal model.  

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Bible
March 11, 2015

Religion and support for birth control health coverage can mix

Even when it comes to policies that have sometimes been characterized as going against Christian views, religious women’s opinions are mixed.

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revolving door
March 10, 2015

Stopping the revolving door: Study finds sepsis survivors return to hospital for preventable reasons

They’re alive thanks to the most advanced care modern hospitals can provide. But for survivors of sepsis, the hospital door often looks like a revolving one, a new study shows. And many of the conditions that send them back to a hospital bed should be preventable.

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Ivan Maillard
March 10, 2015

New strategy for preventing organ transplant rejection shows promise

Researchers at the University of Michigan Life Sciences Institute and U-M Health System Department of Surgery see promise in a new approach to increasing long-term survival after organ transplant — one that’s showing encouraging results in animal models.

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The DICE model aims to reduce psychotropic drug use in dementia
March 03, 2015

Time to “just say no” to behavior-calming drugs for Alzheimer patients? Experts say yes

Doctors write millions of prescriptions a year for drugs to calm the behavior of people with Alzheimer’s disease and other types of dementia. But non-drug approaches actually work better, and carry far fewer risks, experts conclude in a new report.

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cholesterol molecule
March 02, 2015

New views of enzyme structures offer insights into metabolism of cholesterol, other lipids

With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.

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Taylor Swift
February 27, 2015

Shake it off? Not so easy for people with depression, new brain research suggests

Rejected by a person you like? Just “shake it off” and move on, as music star Taylor Swift says. But while that might work for many people, it may not be so easy for those with untreated depression, a new brain study finds.

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Woman veteran wearing camoflage
February 26, 2015

Women veterans with chest pain heavier, more depressed than men

Study shows gender differences in home front battle against heart disease.

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