People with depression or bipolar disorder often feel their thinking ability has gotten “fuzzy”, or less sharp than before their symptoms began. Now, researchers have shown in a very large study that effect is indeed real – and rooted in brain activity differences that show up on advanced brain scans.
For any biotechnology company, getting the first product out of the lab and into patients in a clinical trial is a major milestone, and a cause for celebration. But not many of those companies get to celebrate on the campus where the idea for their product was born and first developed.
Nearly half of American hospitals aren’t taking key steps to prevent a kind of gut infection that kills nearly 30,000 people annually and sickens hundreds of thousands more – despite strong evidence that such steps work, according to a new study.
When a hospital patient’s heart stops, the drama starts, as doctors and nurses work furiously at resuscitation. Some hospitals allow family members to watch, while the majority do not. Now, a study has shown for the first time on a national scale that patients do just as well after a cardiac arrest either way.
If you got hit with any of the ‘intestinal bugs’ that went around this winter, you’ve felt the effects of infectious microbes on your digestive system. But scientists don’t fully understand what’s going on in gut infections like that. Now, a new $6.4 million grant will fuel research based on stem cells to find out.
Two young men in their late teens sit in adjacent rooms of an inner-city emergency room. One is getting care for injuries he suffered in a fight, the other, for a sore throat. A study finds that the one who had been in a fight will have a nearly 60 percent chance of becoming involved in a violent incident involving a firearm within the next two years.
What happens in the moments just before death is widely believed to be a slowdown of the body’s systems as the heart stops beating and blood flow ends. But there's a brainstorm happening, strongly synchronized with heart rhythm. Blocking this brain outflow may change the odds of survival for those who suffer cardiac arrest.
The little voice inside your head that tells you to eat, or stop eating, isn’t a little voice – it’s actually a cluster of about 10,000 specialized brain cells. And now, an international team of scientists has found tiny triggers inside those cells that give rise to this “voice”, and keep it speaking throughout life.
Most neurologists provide face-to-face care of neurology patients, many of whom require extensive evaluation and management. However, a new study finds face-to-face care by neurologists is severely undervalued by Medicare and reimbursed at a substantially lower rate than what Medicare pays doctors for performing tests and procedures.
One year ago, the first Michiganders gained health insurance coverage under the Healthy Michigan Plan, a unique form of Medicaid expansion tailored to the state’s residents. Now, more than 603,000 people have coverage under the plan -- and U-M researchers are hard at work to study how the new coverage affected them, their health care providers, and the state as a whole.
Researchers at the University of Michigan Comprehensive Cancer Center have developed a new drug candidate that shows potential in laboratory studies against a rare type of acute leukemia. And additional studies suggest the same compound could play a role in prostate cancer treatment as well.
An advanced form of life support that takes over for the failing hearts and lungs of critically ill patients saves lives. But for adults, the odds of surviving depend on which hospital provides the life-supporting treatment – with the best odds at ones that use the technique dozens of times a year, a new study finds.
Every day, patients around the country get IV devices placed in their arms, to make it easier to receive medicines or have blood drawn over the course of days or weeks. But these PICC lines, as they’re called, also raise the risk of potentially dangerous blood clots. Now, a U-M team has shown how serious that clot risk really is for hospitalized patients, and what factors put patients at highest risk.
If every new car made in the United States had a built-in blood alcohol level tester that prevented impaired drivers from driving the vehicle, how many lives could be saved, injuries prevented, and injury-related dollars left unspent? Researchers at the University of Michigan Injury Center and the University of Michigan Transportation Research Institute studied the impact of installing these alcohol ignition interlock devices in all newly purchased vehicles over a 15-year period; their estimates of injury prevention and cost savings are significant.
In a randomized phase 3 trial, adrenal cancer patients receiving the investigational drug linsitinib fared no better than patients receiving a placebo. But the researchers noticed a small subset of patients who had significant response and remained on the drug for an extended time.
They’re alive thanks to the most advanced care modern hospitals can provide. But for survivors of sepsis, the hospital door often looks like a revolving one, a new study shows. And many of the conditions that send them back to a hospital bed should be preventable.
Researchers at the University of Michigan Life Sciences Institute and U-M Health System Department of Surgery see promise in a new approach to increasing long-term survival after organ transplant — one that’s showing encouraging results in animal models.
Doctors write millions of prescriptions a year for drugs to calm the behavior of people with Alzheimer’s disease and other types of dementia. But non-drug approaches actually work better, and carry far fewer risks, experts conclude in a new report.
With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.
Rejected by a person you like? Just “shake it off” and move on, as music star Taylor Swift says. But while that might work for many people, it may not be so easy for those with untreated depression, a new brain study finds.