deucravacitinib

Pronunciation: due krav a sye ti nib

Brand: Sotyktu

What is the most important information I should know about deucravacitinib?

Serious infections may occur during treatment with deucravacitinib. Call your doctor right away if you have signs of infection such as: fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.

Deucravacitinib can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

What is deucravacitinib?

Deucravacitinib is used to treat adults with moderate to severe plaque psoriasis.

Deucravacitinib may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking deucravacitinib?

You should not use deucravacitinib if you are allergic to it.

Tell your doctor if you have ever had:

  • liver or kidney disease;
  • hepatitis B or C;
  • high blood levels of fat (triglycerides);
  • any type of cancer;
  • tuberculosis or have been exposed to tuberculosis;
  • if you have an infection that keeps returning or does not go away;
  • if you are being treated for an infection;
  • if you have recently received or are scheduled to receive a vaccine; or
  • if you have high blood pressure, high cholesterol, diabetes, menopause (women), family history of coronary artery disease, being overweight, or being over 50, or if you smoke.

Tell your doctor if you are pregnant or breastfeeding.

How should I take deucravacitinib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take deucravacitinib once every day, with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

You will need medical tests before you start taking deucravacitinib and while taking this medicine.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking deucravacitinib?

Avoid receiving a "live" vaccine. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

What are the possible side effects of deucravacitinib?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Deucravacitinib can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

Also call your doctor at once if you have:

  • signs of infection --fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.

Common side effects may include:

  • cold symptoms such as stuffy nose, sneezing, sore throat;
  • cold sores, sores on your gums, tongue or mouth;
  • folliculitis (redness or crusting around your hair follicles); or
  • acne.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect deucravacitinib?

Other drugs may affect deucravacitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your doctor or pharmacist can provide more information about deucravacitinib.

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