olipudase alfa
What is the most important information I should know about olipudase alfa?
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
What is olipudase alfa?
Olipudase alfa is used to treat people with a genetic disorder called acid sphingomyelinase deficiency (ASMD).
Olipudase alfa may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before receiving olipudase alfa?
Tell your doctor if you have ever had:
- liver disease.
You may need to have a negative pregnancy test before starting this treatment.
May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using olipudase alfa and for at least 14 days after your last dose. Tell your doctor if you become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
How is olipudase alfa given?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Olipudase alfa is injected into a vein.
Ask your doctor or pharmacist if you don't understand how to use an injection.
Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.
Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.
Doses are based on weight. Your dose may change if you gain or lose weight.
You will be watched for a short time to make sure you do not have an allergic reaction.
You will need frequent blood tests to check your liver function.
Follow all storage instructions provided with olipudase alfa. Your pharmacist can provide more information about how to store this medicine.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving olipudase alfa?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of olipudase alfa?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Call your doctor at once if you have:
- liver problems --loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:
- joint pain;
- hives, rash, itching;
- stuffy nose;
- headache;
- cough;
- sore throat;
- feeling like you might pass out;
- eye redness;
- fever, tiredness; or
- diarrhea, stomach pain, vomiting, nausea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect olipudase alfa?
Other drugs may affect olipudase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Where can I get more information?
Your doctor or pharmacist can provide more information about olipudase alfa.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2023 Cerner Multum, Inc. Version: 1.01. Revision date: 11/30/2022.
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.