What is the most important information I should know about iloprost inhalation?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What is iloprost inhalation?
Iloprost inhalation is used to treat pulmonary arterial hypertension (PAH) in adults. This medicine can temporarily improve your symptoms and may improve your ability to exercise.
Iloprost inhalation may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking iloprost inhalation?
Tell your doctor if you have ever had:
- liver disease;
- kidney disease;
- low blood pressure;
- asthma; or
- chronic obstructive pulmonary disease (COPD).
Do not start or stop taking this medicine during pregnancy without your doctor's advice. Having PAH during pregnancy may cause complications in the mother such as heart failure, stroke, or death. Having PAH during pregnancy can also cause complications in the baby such as premature birth, low birthweight, miscarriage, or stillbirth. The benefit of treating PAH may outweigh any risks to the mother or baby.
You should not breastfeed while using iloprost.
How should I use iloprost inhalation?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Do not swallow iloprost inhalation solution. It is to be used only with a nebulizer device.
Iloprost is an inhaled medicine that should be used only with the I-neb ADD System. Do not use iloprost inhalation with any other type of nebulizers.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Iloprost inhalation is usually given 6 to 9 times per day. Follow your doctor's dosing instructions very carefully.
Your doses should not be spaced less than 2 hours apart, even if you feel like the effects of the medicine have worn off in less than 2 hours.
Each ampule (bottle) is for one use only. Throw it away after one use, even if there is still medicine left inside.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include dizziness, headache, nausea, vomiting, diarrhea, or redness in your face.
What should I avoid while using iloprost inhalation?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Avoid allowing anyone else to breathe in this medication while you are inhaling your dose, especially a baby.
Avoid getting this medication in your eyes or on your skin. If this does happen, rinse with water.
What are the possible side effects of iloprost inhalation?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- a light-headed feeling, like you might pass out;
- pounding heartbeats or fluttering in your chest;
- pain or tightness in your jaw;
- unusual bleeding (nosebleeds, bleeding gums);
- pneumonia --fever, chills, cough with mucus, chest pain, feeling short of breath; or
- fluid build-up in or around the lungs --pain when you breathe, feeling short of breath while lying down, wheezing, gasping for breath, cough with foamy mucus, cold and clammy skin, anxiety, rapid heartbeats.
Common side effects may include:
- pneumonia, increased cough, coughing up blood;
- pounding heartbeats;
- low blood pressure, feeling light-headed;
- flu symptoms;
- flushing (warmth, redness, or tingly feeling);
- abnormal liver function tests;
- nausea, vomiting;
- muscle cramps, back pain;
- tongue pain, jaw tightness or pain, trouble chewing or speaking; or
- sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect iloprost inhalation?
Tell your doctor about all other medicines you use, especially:
- blood pressure medication;
- a blood thinner such as warfarin (Coumadin, Jantoven); or
- medication used to prevent blood clots, such as clopidogrel, rivaroxaban, Plavix, Xarelto, and others.
This list is not complete. Other drugs may affect iloprost inhalation, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Where can I get more information?
Your doctor or pharmacist can provide more information about iloprost inhalation.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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