tedizolid (oral/injection)

What is the most important information I should know about tedizolid?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is tedizolid?

Tedizolid is an antibiotic that is used to treat skin infections in adults, including "MRSA" staph infections.

Tedizolid may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using tedizolid?

Tell your doctor if you have recently been sick with diarrhea, a fever, cold or flu symptoms, cough, or sore throat.

Tell your doctor if you have ever had diarrhea while taking antibiotics.

How should I use tedizolid?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Tedizolid oral is taken by mouth. Take this medicine at the same time each day, with or without food.

Tedizolid injection is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. The injection must be given slowly, and the infusion can take at least 1 hour to complete.

Tedizolid injection must be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine. Use only the diluent provided with your medicine.

Gently swirl but do not shake the mixed medicine. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

Use tedizolid for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Tedizolid will not treat a viral infection such as the flu or a common cold.

Keep each tablet in its blister pack until you are ready to take it. Prepare your tedizolid injection dose only when you are ready to give an injection.

Each single-use vial (bottle) of tedizolid injection is for one use only. Throw it away after one use, even if there is still medicine left inside.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 8 hours. Do not use two doses at one time. Even if you skip a dose, keep taking the medicine each day until it is gone.

What happens if I overdose?

What should I avoid while using tedizolid?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

What are the possible side effects of tedizolid?

• severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
• numbness or tingling;
• vision problems, severe headache or pain behind your eyes;
• sores or white patches in your mouth or on your skin;
• vaginal itching or discharge;
• fast or pounding heartbeats; or
• low blood cell counts --fever, chills, tiredness, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common side effects may include:

• nausea, vomiting, diarrhea;
• headache;
• dizziness; or
• pain, swelling, bruising, redness, or a hard lump where a tedizolid injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect tedizolid?

Tell your doctor about all your other medicines, especially:

• methotrexate;
• rosuvastatin (Crestor); or
• topotecan.

This list is not complete. Other drugs may affect tedizolid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about tedizolid.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 2.02. Revision date: 10/8/2019.