John Robert Charpie MD, PhD

Professor, Pediatrics
Pediatric Cardiology, Pediatrics
Clinical Interests:

Pediatric cardiology, pediatric cardiothoracic intensive care, congenital heart disease.

Video profile



Medical School or Training

  • Boston University, 1990


  • Massachusetts General Hospital, Pediatrics, MA, 1992


  • Pediatric Cardiology, University of Michigan Health System, 1995

Professional Organizations

  • American College of Cardiology

  • American Academy of Pediatrics

  • American Heart Association

  • Society for Pediatric Research

  • Pediatric Cardiac Intensive Care Society

Board Certification

  • Pediatric Cardiology


  1. Myocardial ischemia-reperfusion injury
  2. Acute and long-term outcomes following congenital heart surgery
  3. Endothelial dysfunction (nitric oxide and vascular oxidative stress)
  4. Clinical trials in congenital heart disease
  5. Hypertension


John R. Charpie, M.D., Ph.D. is Division Director and Amnon Rosenthal Collegiate Professor of Pediatric Cardiology. His clinical interests and expertise are in pediatric cardiac intensive care for infants, children and young adults with congenital and acquired heart disease. Dr. Charpie’s research focuses on myocardial ischemia-reperfusion injury associated with cardiopulmonary bypass, and endothelial dysfunction in children. As a cardiac intensivist, Dr. Charpie is also interested in examining early and late outcomes following congenital heart disease surgery, and novel interventions aimed at improving morbidity and mortality including antioxidants and therapeutic hypothermia among others. Dr. Charpie serves as a Principal Investigator or Co-investigator for several government and industry-sponsored studies in pediatric cardiology.

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