Francis D. Pagani, M.D., Ph.D., is the Otto Gago MD Endowed Professor in Cardiac Surgery. Dr. Paganis clinical focus includes surgical therapies for advanced heart failure including heart transplantation and mechanical circulatory support and complex re-operative surgery for valvular heart disease. Dr. Pagani also serves as the surgical lead for the multidisciplinary Hypertrophic Cardiomyopathy program and has an active practice in surgical treatments (myectomies) for this disorder. Dr. Paganis research focuses on the use of mechanical circulatory support in the treatment of end-stage heart disease and use of stem cell transplantation for myocardial regeneration. The Center for Circulatory Support (VAD Program), under Dr. Pagani's direction, is one of the most recognized and well-respected programs in the nation.