With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.
Rejected by a person you like? Just “shake it off” and move on, as music star Taylor Swift says. But while that might work for many people, it may not be so easy for those with untreated depression, a new brain study finds.
How can we keep more people from joining the ranks of the 29 million Americans already diagnosed with diabetes? What if we could tell with precision who has the highest risk of developing the disease, and figure out which preventive steps are most likely to help each of them individually? Researchers have just released a “precision medicine” approach to diabetes prevention that could do just that – using existing information, and without needing new genetic tests.
Sometimes, science means staying awake for two days straight. But losing sleep is a small sacrifice to make, if you want to learn more about tiny bacteria that sicken half a million Americans each year, kill more than 14,000 of them, and rack up $4.8 billion in health care costs.
When patients with glaucoma switched from a brand name drug to its generic counterpart, they were more likely to take their medication as directed compared to those who remained on the brand name drug, according to a new U-M Kellogg Eye Center study.
What should doctors wear? And how does something as simple as their choice of a suit, scrubs or slacks influence how patients view them? A new analysis takes a comprehensive look – and finds that the answer isn’t as simple as you might think.
A tragic accident 32 years ago forever altered the lives of an entire prominent Michigan auto industry family, as a beloved wife and mother suffered a devastating traumatic brain injury, or TBI. Now, the Massey family has invested in the hope that University of Michigan medical and scientific teams can spare other families what they endured.
If you’re an older person having a major operation these days, it is very likely that your hospital is receiving a “report card” on their performance. These reports are designed to prompt hospitals to improve in areas where they perform poorly. That’s the good news. The not-so-good news: Those “report cards” do not seem to be making things better for patients.
A U-M alumna who sought to avoid passing a deadly disease to her son has given scientists a gift that could help many more families affected by the same disease: an embryo that has allowed U-M researchers to produce stem cells and nerve cells that contain the crucial disease-causing genetic defect.
A new test can guide treatment for patients with graft versus host disease (GVHD), an often life-threatening complication of bone marrow and stem cell transplants, according to research from the University of Michigan published in Lancet Haematology this month.