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U-M Cancer Center gets $28.4 million grant from NCI

‘Comprehensive cancer center’ status also renewed

ANN ARBOR, Mich. — The National Cancer Institute has awarded the University of Michigan Comprehensive Cancer Center a grant worth $28.4 million over five years. At the same time, the center’s designation as a “comprehensive cancer center” was renewed.

The grant is a renewal of the Cancer Center’s core support grant, provided as part of the NCI’s cancer centers program. U-M has received NCI funding for its Cancer Center since 1988. The new grant will fund the center through 2017.

“With this grant and the resources of the University of Michigan, including new opportunities at the North Campus Research Complex, our Cancer Center is poised to bring great advances to cancer treatment and offer new opportunities for our patients,” says Max S. Wicha, M.D., director of the U-M Comprehensive Cancer Center and Distinguished Professor of Oncology.

The funding will allow ongoing research in 13 basic, clinical and prevention/control programs, including in cancer stem cells, experimental therapeutics and cancer genetics. It also provides support for 18 core shared research services, including the center’s clinical trials operations. NCI reviewers noted particular strengths in prostate cancer, breast cancer and cancer stem cell biology.

The Cancer Center submitted a 1,937-page grant renewal to the NCI and underwent a rigorous two-day site visit by reviewers in fall 2011. Overall, U-M received an “outstanding” rating. Reviewers commented that the Cancer Center has had “a significant impact not only on cancer research but increasingly on the burden of cancer.”

“The [University of Michigan] is a strong Cancer Center that has made, and should continue to make, major contributions to cancer research,” the reviewers noted.

To earn the designation of “comprehensive cancer center,” an institution must participate in basic, clinical, and prevention and control research, with strong interactions among those areas. A center must also provide public information, education and outreach programs. U-M is one of two comprehensive cancer centers in Michigan and one of 41 across the country.

The review committee approved a 63 percent increase in funding over the prior grant, which was renewed in 2006. But due to federal budget cuts and a shrinking pool of money at the National Institutes of Health, funding remained essentially flat, despite an outstanding score from the NCI reviewers.

“Federal funding has allowed us to make significant progress against cancer. But this is still a devastating disease with a profound physical, emotional and financial impact on patients and their loved ones. Continued federal support is crucial to advancing our laboratory discoveries and mounting the innovative clinical trials needed to test the most promising new treatments and bring more effective options to our patients,” Wicha says.

“Funding from the National Institutes of Health is flat across the board, and it’s becoming harder for investigators to get grants,” Wicha adds. “Despite that, our Cancer Center has done extremely well and continues to be one of the top-funded programs in the country.”

The University of Michigan received the most NCI funding in the nation among academic medical centers. In 2011, the Cancer Center had a total of $79 million in NCI grants.

Cancer statistics: 1.6 million Americans will be diagnosed with cancer this year and 577,190 will die from the disease, according to the American Cancer Society

Funding: National Cancer Institute of the National Institutes of Health Award Number P30CA046592

U-M Cancer AnswerLine, 800-865-1125
Clinical trials at U-M

About the University of Michigan Comprehensive Cancer Center:
The University of Michigan Comprehensive Cancer Center has 337 faculty members delivering compassionate care to today’s patients and researching ways to improve treatments for tomorrow’s patients. It’s our mission: the conquest of cancer through innovation and collaboration. The U-M Comprehensive Cancer Center is among the top-ranked national cancer programs for both research and patient care. It is one of 41 centers designated "comprehensive" by the National Cancer Institute and one of 21 institutions that make up the National Comprehensive Cancer Network, which sets national guidelines for consistent, high-quality and cost-effective cancer care.

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