In Hirschsprung's disease, certain nerve cells (ganglion cells) in a portion of the colon are missing. Because the muscles in that area can't relax, the muscle contractions that normally push food and digestive waste through that part of the colon can't occur. The picture on the right shows a colon in which the rectum lacks ganglion nerve cells, causing swelling in the area above it.
Current as of:
May 27, 2020
Author: Healthwise Staff Medical Review: John Pope MD - Pediatrics Kathleen Romito MD - Family Medicine Brad W. Warner MD - Pediatric Surgery
Medical Review:John Pope MD - Pediatrics & Kathleen Romito MD - Family Medicine & Brad W. Warner MD - Pediatric Surgery