patisiran
What is the most important information I should know about patisiran?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Tell your doctor if you use other medicines or have other medical conditions or allergies.
What is patisiran?
Patisiran is used to treat adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (damage of multiple nerves throughout the body).
Patisiran may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before using patisiran?
Before using patisiran tell your doctor about all your medical conditions or allergies.
Patisiran may harm an unborn baby. Tell your doctor if you are pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of patisiran on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
How is patisiran given?
Patisiran is given as an infusion into a vein. A healthcare provider will give you this injection once every 3 weeks.
This medicine must be given slowly, and the infusion can take about 80 minutes to complete.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when patisiran is injected.
You may be given other medications to help prevent serious side effects or an infusion reaction.
Your doctor may have you take vitamin A while you are using patisiran. Take only the amount of vitamin A your doctor has prescribed, especially if you are pregnant. An overdose of vitamin A can cause vision problems or other serious side effects.
Call your doctor at once if you have vision problems (especially at night) while you are taking patisiran.
Patisiran doses are based on weight. Your dose needs may change if you gain or lose weight.
You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective. You may also need frequent eye exams.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your patisiran injection.
What happens if I overdose?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while using patisiran?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of patisiran?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Common side effects may include:
- cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect patisiran?
Other drugs may affect patisiran, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2023 Cerner Multum, Inc. Version: 4.02. Revision date: 11/13/2022.
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.