prucalopride

Pronunciation: proo KAL oh pride

Brand: Motegrity

What is the most important information I should know about prucalopride?

You should not use prucalopride if you have a blockage in your intestines, Crohn's disease, ulcerative colitis, or intestinal perforation.

What is prucalopride?

Prucalopride is used to treat chronic idiopathic constipation (constipation without a known cause).

Prucalopride may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking prucalopride?

You should not use prucalopride if you are allergic to it, or if you have:

  • a blockage in your intestines;
  • severe constipation;
  • inflammatory bowel disease (Crohn's disease, ulcerative colitis);
  • toxic megacolon; or
  • perforation (a hole or tear) of your intestines.

Tell your doctor if you have ever had:

  • kidney disease;
  • depression;
  • a mood disorder; or
  • suicidal thoughts.

Tell your doctor if you are pregnant or breast-feeding.

Prucalopride is not approved for use by anyone younger than 18 years old.

How should I take prucalopride?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take prucalopride with or without food.

Store prucalopride in the original container at room temperature, away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose may cause severe diarrhea.

What should I avoid while taking prucalopride?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of prucalopride?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using prucalopride and call your doctor at once if you have:

  • unusual changes in mood or behavior;
  • ongoing or worsening depression;
  • thoughts about suicide or hurting yourself; or
  • if you feel sad or hopeless.

Common side effects may include:

  • nausea, vomiting, diarrhea;
  • stomach pain, bloating, gas;
  • headache;
  • dizziness; or
  • feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect prucalopride?

Other drugs may affect prucalopride, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about prucalopride.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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prucalopride