What is the most important information I should know about idarubicin?
Idarubicin can increase your risk of bleeding or infection. Call your doctor if you have unusual bruising or bleeding, or new signs of infection (fever, chills, tiredness).
Idarubicin may cause dangerous effects on your heart, especially if you have heart problems, if you have received certain cancer drugs in the past, or if you are over 60.
Seek medical attention right away if you have chest pain, irregular heartbeats, shortness of breath, swelling, or rapid weight gain.
What is idarubicin?
Idarubicin is used in combination chemotherapy to treat acute myeloid leukemia (AML), a type of blood cancer.
Idarubicin may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before receiving idarubicin?
Idarubicin may cause dangerous effects on your heart. especially if you have heart problems, if you have received certain cancer drugs in the past, or if you are over 60.
Tell your doctor if you have ever had:
- heart problems;
- radiation treatment;
- chemotherapy with doxorubicin, daunorubicin, epirubicin, idarubicin, or mitoxantrone;
- bone marrow suppression;
- liver or kidney disease;
- anemia (low red blood cells); or
- sepsis (a severe reaction to an infection).
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using this medicine.
How is idarubicin given?
Idarubicin is given as an infusion into a vein. A healthcare provider will give you this injection.
Idarubicin is usually given together with other cancer medicines. You may be given other medications to prevent nausea, vomiting, or infections.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when idarubicin is injected.
If any of this medication accidentally gets on your skin, wash it thoroughly with soap and warm water.
Idarubicin can increase your risk of bleeding or infection. You will need frequent medical tests. Your liver, kidney, and heart function may also need to be checked.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your idarubicin injection.
What happens if I overdose?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while receiving idarubicin?
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
What are the possible side effects of idarubicin?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Idarubicin may cause dangerous effects on your heart. Tell doctor right away if you have chest pain, shortness of breath (even with mild exertion), swelling, or rapid weight gain.
Call your doctor at once if you have:
- irritation or skin changes where the injection was given;
- fever, chills, tiredness, feeling light-headed or short of breath.
- pale skin, easy bruising or bleeding (nosebleeds, bleeding gums);
- pain, blisters, bleeding, or severe rash on the palms of your hands or the soles of your feet;
- sores or white patches in or around your mouth; or
- severe nausea, vomiting, stomach cramps, or diarrhea.
Common side effects may include:
- nausea, vomiting, stomach pain, diarrhea;
- mouth sores;
- rash; or
- hair loss.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect idarubicin?
Tell your doctor about all other cancer medicines you have received in the past 7 months, especially:
- paclitaxel; or
This list is not complete. Other drugs may affect idarubicin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Where can I get more information?
Your doctor or pharmacist can provide more information about idarubicin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2022 Cerner Multum, Inc. Version: 3.01. Revision date: 12/10/2020.