Pronunciation: METH il DOE pa
250 mg, round, white, imprinted with N 11
500 mg, round, white, imprinted with N77
500 mg, oval, beige, imprinted with 421, MYLAN
250 mg, round, beige, imprinted with 611, MYLAN
500 mg, round, orange, imprinted with AHI, M23
250 mg, round, beige, imprinted with 611, MYLAN
250 mg, round, yellow, imprinted with WPPH, 152
250 mg, round, white, imprinted with Z 2931
500 mg, round, white, imprinted with Z 2932
500 mg, oblong, beige, imprinted with 421, MYLAN
What is the most important information I should know about methyldopa?
You should not use methyldopa if you have liver disease (especially cirrhosis), or a history of liver problems caused by taking methyldopa.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
What is methyldopa?
Methyldopa lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels (veins and arteries) to relax (widen).
Methyldopa is used to treat hypertension (high blood pressure).
Methyldopa may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking methyldopa?
You should not use methyldopa if you are allergic to it, or if you have:
- liver disease (especially cirrhosis); or
- a history of liver problems caused by taking methyldopa.
Do not use methyldopa if you have used a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Tell your doctor if you have ever had:
- liver disease;
- kidney disease (or if you are on dialysis);
- heart disease, angina (chest pain); or
- a heart attack or stroke.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether methyldopa will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
How should I take methyldopa?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Your blood pressure will need to be checked often. Your liver function may also need to be checked.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
Methyldopa can affect the results of certain medical tests. Tell any doctor who treats you that you are using methyldopa.
If you need surgery or a blood transfusion, tell your caregivers ahead of time that you are using methyldopa.
Methyldopa doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include extreme drowsiness, vomiting, slow heartbeats, or fainting.
What should I avoid while taking methyldopa?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
What are the possible side effects of methyldopa?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- a light-headed feeling, like you might pass out;
- pale or yellowed skin, dark colored urine, fever, confusion or weakness;
- uncontrolled or involuntary muscle movements;
- heart problems --swelling, rapid weight gain, feeling short of breath; or
- signs of liver or pancreas problems --loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes).
Common side effects may include:
- weakness; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect methyldopa?
Tell your doctor about all other medicines you use, especially:
- ferrous gluconate, ferrous sulfate, or other medicine that contains iron;
- lithium; or
- any other blood pressure medications.
This list is not complete. Other drugs may affect methyldopa, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2023 Cerner Multum, Inc. Version: 8.01. Revision date: 9/17/2018.