Dr. Greden's clinical and research activities have emphasized the study of the longitudinal course of depression, linkages between stress hormones and depressive recurrences, and clinical strategies for preventing such recurrences. He has published more than 268 scientific papers, edited a number of scientific books including "Treatment of Recurrent Depression," and has been acknowledged in various listings of the "The Best Doctors," and the "Top 100 Psychiatrists" in America. He has been a devoted educator, having delivered more than 300 invited presentations on depression and other topics nationally and internationally and was twice acknowledged as "Teacher of the Year," at the University of Michigan Medical School.