Medical School or Training
University of Heidelberg, 1992
University of Munich Medical School, Internal Medicine, 1999
Internal Medicine Nephrology, University of Munich Medical School, 2002
Australian-New Zealand Socitey of Nephrology
National Kidney Foundation
American Heart Association
German Society of Nephrology
American Society of Nephrologists
European Kidney Research Association
The major research focus of my laboratory is on the use of modern molecular biology tools to better understand disease mechanism activated in human renal biopsies. We currently evaluate these novel tools for molecular diagnosis of kidney and transplant failure in international multicenter studies.The longstanding interest in my group has been on glomerular filtration barrier failure. Using cell and molecular biology approaches we have identified novel cell-matrix signaling molecules activated in glomerular failure. Intervening with their function might evolve into a novel therapeutic strategy and we are currently evaluate this approach with small molecule inhibitors in vitro and in vivo and in cell type specific knock out mice.
Dr. Kretzler graduated from the University of Heidelberg, Germany. He completed his internal medicine residency at the University of Munich, Germany and a nephrology fellowship at the University of Michigan. He is a past research fellow in physiology and nephrology at the University of Michigan. Dr. Kretzler is board-certified in internal medicine and nephrology. He has a special interest in the diagnosis and management of glomerular diseases.