National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Pemphigus is not the name you expected.
- drug-induced pemphigus
- endemic pemphigus (fogo selvagem)
- pemphigus erythematosus (Senear-Usher syndrome)
- pemphigus foliaceus
- pemphigus vegetans
- pemphigus vulgaris
Pemphigus is a general term for a group of rare autoimmune blistering skin disorders. Autoimmune disorders occur when the body's own immune system mistakenly attacks healthy tissue. The symptoms and severity associated with the various forms of pemphigus vary. All forms of pemphigus are characterized by the development of blistering eruptions on the outer layer of the skin (epidermis). In pemphigus vulgaris, lesions also develop on the mucous membranes such as those lining the inside the mouth. Mucous membranes are the thin, moist coverings of many of the body's internal surfaces. If left untreated, pemphigus will usually be fatal. The exact cause of pemphigus is unknown.
The term pemphigus is a general term for a group of related autoimmune blistering skin diseases. The two main types of pemphigus are pemphigus vulgaris and pemphigus foliaceus. Each type has subtypes. Additional disorders are sometimes classified as pemphigus including paraneoplastic pemphigus and pemphigus IgA. Some physicians consider these disorders similar, yet distinct, autoimmune blistering disorders with different causes and clinical, immunological and microscopic tissue (histological) features. Pemphigoid is a general term for a different group of skin disorders. These other disorders are discussed in the related disorders section of this report.
American Autoimmune Related Diseases Association, Inc.
22100 Gratiot Ave.
Eastpointe, MI 48021
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
One AMS Circle
Bethesda, MD 20892-3675
International Pemphigus & Pemphigoid Foundation
2701 Cottage Way
Sacramento, CA 95825
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Autoimmune Information Network, Inc.
PO Box 4121
Brick, NJ 08723
Australasian Blistering Diseases Foundation
St. George Hospital,
Department of Dermatology
Sydney, NSW 2217
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This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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Last Updated: 11/15/2012
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