Pleurisy Root

Uses

Botanical names:
Asclepias tuberosa

Parts Used & Where Grown

As its common name indicates, the root of pleurisy root is used as medicine. This brilliant-orange-flowered herb is native to and continues to grow primarily in the southwestern and midwestern United States. Many plants similar to pleurisy root are known as milkweeds because they produce a milky sap—something pleurisy root does not do.

What Are Star Ratings?

This supplement has been used in connection with the following health conditions:

Used forWhy
1 Star
Bronchitis
Refer to label instructions
Pleurisy root is traditionally used to loosen bronchial secretions and is thought to be helpful against all types of respiratory infections.

Expectorant herbs help loosen bronchial secretions and make elimination of mucus easier. Numerous herbs are traditionally considered expectorants, though most of these have not been proven to have this effect in clinical trials. is an expectorant and is thought to be helpful against all types of respiratory infections. It is traditionally employed as an expectorant for bronchitis. However, owing to the cardiac glycosides it contains, pleurisy root may not be safe to use if one is taking heart medications. This herb should not be used by pregnant women.

1 Star
Pleurisy
Refer to label instructions
Pleurisy root has a history of use internally as a remedy for lung infections and other problems, such as pleurisy and pneumonia.
Pleurisy root was used by Native American tribes both internally as a remedy for pulmonary infections and topically to treat wounds. The Eclectic physicians seized upon these ideas and continued to use the plant primarily for lung problems such as pleurisy and pneumonia. It was also used as a diaphoretic (a substance that causes sweating) for all manner of infections. Pleurisy root was an official medicine in the United States Pharmacopoeia from 1820 to 1905.
1 Star
Pneumonia
Refer to label instructions
Pleurisy root has a history of use internally as a remedy for lung infections and other problems, such as pneumonia and pleurisy.
Pleurisy root was used by Native American tribes both internally as a remedy for pulmonary infections and topically to treat wounds. The Eclectic physicians seized upon these ideas and continued to use the plant primarily for lung problems such as pleurisy and pneumonia. It was also used as a diaphoretic (a substance that causes sweating) for all manner of infections. Pleurisy root was an official medicine in the United States Pharmacopoeia from 1820 to 1905.

Traditional Use (May Not Be Supported by Scientific Studies)

Pleurisy root was used by Native American tribes both internally as a remedy for pulmonary infections and topically to treat wounds.1 The Eclectic physicians seized upon these ideas and continued to use the plant primarily for lung problems such as pleurisy and pneumonia. It was also used as a diaphoretic (a substance that causes sweating) for all manner of infections.2 Pleurisy root was an official medicine in the United States Pharmacopoeia from 1820 to 1905.3

How It Works

Botanical names:
Asclepias tuberosa

How It Works

Insufficient work has been done to identify the active constituents in pleurisy root or its medicinal actions. No human studies have been conducted to determine whether it is effective for any indication. It is still used by herbalists and some physicians trained in herbal medicine as a diaphoretic (promotes sweating), and for lung infections and conditions of the pleura that lines the lungs.4

How to Use It

A pleurisy root tea can be made by lightly simmering one teaspoon of the dried, chopped root in one pint of water for 10 to 15 minutes. One cup of this tea can be drunk twice per day.5 Alternately, 1 to 2 ml of tincture of the fresh root can be used three times per day.6

Interactions

Botanical names:
Asclepias tuberosa

Interactions with Supplements, Foods, & Other Compounds

At the time of writing, there were no well-known supplement or food interactions with this supplement.

Interactions with Medicines

Certain medicines interact with this supplement.

Types of interactions:BeneficialAdverseCheck

Replenish Depleted Nutrients

  • none

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • Acebutolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Amlodipine-Benazepril

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Atenolol

    As pleurisy root and other plants in the Aesclepius species contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as atenolol.

  • Betaxolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Bisoprolol

    As pleurisy root and other plants in the Aesclepius species contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as bisoprolol.

  • Digoxin

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as digoxin.

  • Labetalol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Nadolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Propranolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Sotalol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Timolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

Explanation Required

  • Amlodipine

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Bepridil

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Carteolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta blockers.

  • Diltiazem

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Felodipine

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Isradipine

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Levobunolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Metipranolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta blockers.

  • Metoprolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Nebivolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta blockers.

  • Nicardipine

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Nifedipine

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Nimodipine

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Nisoldipine

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

  • Penbutolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Pindolol

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.

  • Verapamil

    As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.

Side Effects

Botanical names:
Asclepias tuberosa

Side Effects

At the recommended amounts, pleurisy root generally has no adverse effects. Excessive intake (1 tablespoon or more of the root at one time) can cause intestinal cramping, nausea, vomiting, and diarrhea.7 Pleurisy root should be avoided by pregnant women as it may stimulate uterine contractions.8

References

1. Vogel VJ. American Indian Medicine. Norman: University of Oklahoma Press, 1970:287-8.

2. Felter HW, Lloyd JU. King's American Dispensatory, 18th ed, vol 1. Portland, OR: Eclectic Medical Publications, 1898, 1983:288-1.

3. Vogel VJ. American Indian Medicine. Norman: University of Oklahoma Press, 1970:287-8.

4. Moore M. Medicinal Plants of the Mountain West. Santa Fe: Museum of New Mexico Press, 1979:130.

5. Moore M. Medicinal Plants of the Mountain West. Santa Fe: Museum of New Mexico Press, 1979:130.

6. Felter HW, Lloyd JU. King's American Dispensatory, 18th ed, vol 1. Portland, OR: Eclectic Medical Publications, 1898, 1983:288-1.

7. Moore M. Medicinal Plants of the Mountain West. Santa Fe: Museum of New Mexico Press, 1979:130.

8. Brinker F. Herb Contraindications and Drug Interactions. Sandy, OR: Eclectic Medical Publications, 1998, 112-3.

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