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Zafirlukast is used in the prevention and treatment of mild to severe asthma, seasonal allergic asthma, exercise-induced asthma, and aspirin-induced asthma. It belongs to a class of drugs called leukotriene-receptor antagonists (LTRA).
Common brand names:Accolate
Summary of Interactions with Vitamins, Herbs, & Foods
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Potential Negative Interaction
Willow bark (Salix alba) contains salicin, a substance similar to aspirin. Research has shown that aspirin significantly increases blood levels of zafirlukast,1 which would increase the likelihood of side effects from zafirlukast. The same thing could theoretically happen if people took willow bark along with zafirlukast, although no studies have investigated this specific interaction. People may want to avoid combining willow bark with zafirlukast due to the possibility of increased side effects.The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Last Review: 03-18-2015
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