pioglitazone (oral)

Pronunciation: PYE o GLIT a zone

Brand: Actos

Pioglitazone Hydrochloride

slide 1 of 26, Pioglitazone Hydrochloride,

45 mg, round, white, imprinted with ACTOS, 45

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 2 of 26, Pioglitazone Hydrochloride,

30 mg, round, white, imprinted with ACTOS, 30

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 3 of 26, Pioglitazone Hydrochloride,

15 mg, round, white, imprinted with ACTOS, 15

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 4 of 26, Pioglitazone Hydrochloride,

15 mg, round, white, imprinted with TEVA, 7271

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 5 of 26, Pioglitazone Hydrochloride,

30 mg, round, white, imprinted with TEVA, 7272

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 6 of 26, Pioglitazone Hydrochloride,

45 mg, round, white, imprinted with TEVA, 7273

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 7 of 26, Pioglitazone Hydrochloride,

15 mg, round, white, imprinted with M 48

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 8 of 26, Pioglitazone Hydrochloride,

30 mg, round, white, imprinted with M 228

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 9 of 26, Pioglitazone Hydrochloride,

45 mg, round, white, imprinted with M 318

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 10 of 26, Pioglitazone Hydrochloride,

15 mg, round, white, imprinted with 140, 15

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 11 of 26, Pioglitazone Hydrochloride,

15 mg, round, white, imprinted with P, 15

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 12 of 26, Pioglitazone Hydrochloride,

30 mg, round, white, imprinted with P10, 30

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 13 of 26, Pioglitazone Hydrochloride,

45 mg, round, white, imprinted with P10, 45

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 14 of 26, Pioglitazone Hydrochloride,

30 mg, round, white, imprinted with ML87

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Pioglitazone Hydrochloride

slide 15 of 26, Pioglitazone Hydrochloride,

15 mg, round, white, imprinted with 31, H

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 16 of 26, Pioglitazone Hydrochloride,

30 mg, round, white, imprinted with 32, H

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 17 of 26, Pioglitazone Hydrochloride,

45 mg, round, white, imprinted with 33, H

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Actos

slide 18 of 26, Actos,

15 mg, round, white, imprinted with ACTOS, 15

Image of Actos
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Actos

slide 19 of 26, Actos,

30 mg, round, white, imprinted with ACTOS, 30

Image of Actos
slide 19 of 26

Actos

slide 20 of 26, Actos,

45 mg, round, white, imprinted with ACTOS, 45

Image of Actos
slide 20 of 26

Actos

slide 21 of 26, Actos,

15 mg, round, white, imprinted with ACTOS, 15

Image of Actos
slide 21 of 26

Actos

slide 22 of 26, Actos,

30 mg, round, white, imprinted with ACTOS, 30

Image of Actos
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Actos

slide 23 of 26, Actos,

45 mg, round, white, imprinted with ACTOS, 45

Image of Actos
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Pioglitazone Hydrochloride

slide 24 of 26, Pioglitazone Hydrochloride,

15 mg, round, white, imprinted with H, 31

Image of Pioglitazone Hydrochloride
slide 24 of 26

Pioglitazone Hydrochloride

slide 25 of 26, Pioglitazone Hydrochloride,

30 mg, round, white, imprinted with H, 32

Image of Pioglitazone Hydrochloride
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Pioglitazone Hydrochloride

slide 26 of 26, Pioglitazone Hydrochloride,

45 mg, round, white, imprinted with H, 33

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What is the most important information I should know about pioglitazone?

Pioglitazone can cause or worsen congestive heart failure. You should not use this medicine if you have severe or uncontrolled heart failure.

Stop using this medicine and call your doctor at once if you have shortness of breath (especially when lying down), unusual tiredness, swelling, or rapid weight gain.

What is pioglitazone?

Pioglitazone is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Pioglitazone is not for treating type 1 diabetes.

Pioglitazone may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking pioglitazone?

You should not use this medicine if you are allergic to pioglitazone, or if you have:

  • severe or uncontrolled heart failure; or
  • diabetic ketoacidosis (call your doctor for treatment).

This medication may increase your risk of developing bladder cancer. Talk with your doctor about your specific risk.

Tell your doctor if you have ever had:

  • congestive heart failure or heart disease;
  • a heart attack or stroke;
  • eye problems caused by diabetes;
  • bladder cancer; or
  • liver disease.

Pioglitazone may increase your risk of serious heart problems, but not treating your diabetes can also damage your heart and other organs. Talk to your doctor about the risks and benefits of this medicine.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

Pioglitazone may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

Women may be more likely to have a broken bone while using pioglitazone. Talk with your doctor about ways to keep your bones healthy.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Pioglitazone is not approved for use by anyone younger than 18 years old.

How should I take pioglitazone?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Pioglitazone is usually taken once daily, with or without food.

You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

Pioglitazone is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

What should I avoid while taking pioglitazone?

Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

What are the possible side effects of pioglitazone?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using pioglitazone and call your doctor at once if you have symptoms of liver damage: nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).

Call your doctor at once if you have:

  • shortness of breath (especially when lying down), unusual tiredness, swelling, rapid weight gain;
  • pink or red urine, painful or difficult urination, new or worsening urge to urinate;
  • changes in your vision; or
  • sudden unusual pain in your hand, arm, or foot.

Some people taking this medicine have had bladder cancer, but it is not clear if pioglitazone was the actual cause.

Common side effects may include:

  • headache;
  • muscle pain; or
  • cold symptoms such as stuffy nose, sinus pain, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect pioglitazone?

Tell your doctor if you use insulin. Taking pioglitazone while you are using insulin may increase your risk of serious heart problems.

Many drugs can affect pioglitazone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about pioglitazone.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.