promethazine (oral)

Pronunciation: pro METH a zeen

Brand: Phenergan

Promethazine Hydrochloride

slide 1 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with 5307, DAN DAN

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 2 of 30, Promethazine Hydrochloride,

50 mg, round, white, imprinted with 5319, DAN

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 3 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with GG 225

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 4 of 30, Promethazine Hydrochloride,

50 mg, round, pink, imprinted with GG 235

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 5 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with K 3

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 6 of 30, Promethazine Hydrochloride,

50 mg, round, pink, imprinted with K 4

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 7 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with Z C 0 2

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 8 of 30, Promethazine Hydrochloride,

12.5 mg, round, pink, imprinted with 107

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 9 of 30, Promethazine Hydrochloride,

50 mg, round, pink, imprinted with 109

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 10 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with K3

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 11 of 30, Promethazine Hydrochloride,

50 mg, round, pink, imprinted with K 4

Image of Promethazine Hydrochloride
slide 11 of 30

Promethazine Hydrochloride

slide 12 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with GG 225

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 13 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with AN 521

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 14 of 30, Promethazine Hydrochloride,

12.5 mg, round, white, imprinted with AN, 745

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 15 of 30, Promethazine Hydrochloride,

12.5 mg, round, white, imprinted with ZC 01

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 16 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with Z C 0 2

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 17 of 30, Promethazine Hydrochloride,

50 mg, round, white, imprinted with ZC 03

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 18 of 30, Promethazine Hydrochloride,

12.5 mg, round, white, imprinted with C51

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 19 of 30, Promethazine Hydrochloride,

12.5 mg, round, white, imprinted with ZC 01

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 20 of 30, Promethazine Hydrochloride,

12.5 mg, round, white, imprinted with ZC 01

Image of Promethazine Hydrochloride
slide 20 of 30

Promethazine Hydrochloride

slide 21 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with AN 521

Image of Promethazine Hydrochloride
slide 21 of 30

Promethazine Hydrochloride

slide 22 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with 59911 5872

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 23 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with GG 225

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 24 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with C52

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 25 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with Z C 0 2

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 26 of 30, Promethazine Hydrochloride,

25 mg, round, white, imprinted with 5307, DAN DAN

Image of Promethazine Hydrochloride
slide 26 of 30

Promethazine Hydrochloride

slide 27 of 30, Promethazine Hydrochloride,

50 mg, round, pink, imprinted with AN 522

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 28 of 30, Promethazine Hydrochloride,

50 mg, round, white, imprinted with 59911, 5873

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 29 of 30, Promethazine Hydrochloride,

50 mg, round, white, imprinted with C53

Image of Promethazine Hydrochloride
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Promethazine Hydrochloride

slide 30 of 30, Promethazine Hydrochloride,

50 mg, round, white, imprinted with ZC, 03

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What is the most important information I should know about promethazine?

Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children.

What is promethazine?

Promethazine is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine is not for use in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections.

Promethazine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking promethazine?

Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age.

You should not take this medicine if you are allergic to promethazine or to similar medicines such as chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, or trifluoperazine.

Tell your doctor if you have ever had:

  • asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder;
  • a history of seizures;
  • a weak immune system (bone marrow depression);
  • glaucoma;
  • enlarged prostate or problems with urination;
  • stomach ulcer or obstruction;
  • heart disease or high blood pressure;
  • liver disease; or
  • if you have ever had a serious side effect while using promethazine or any other phenothiazine.

Tell your doctor if you are pregnant or breastfeeding.

How should I take promethazine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Promethazine is often taken at bedtime or before meals. For motion sickness, promethazine is usually started within 1 hour before traveling. When used for surgery, promethazine is usually taken the night before the surgery.

How often you take this medicine and the timing of your dose will depend on the condition being treated.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

If a child is using this medicine, tell your doctor if the child has any changes in weight. Promethazine doses are based on weight in children, and any changes may affect your child's dose.

Call your doctor if your symptoms do not improve, or if they get worse while using promethazine.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using promethazine.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).

What should I avoid while taking promethazine?

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Drinking alcohol can increase certain side effects of promethazine.

Avoid exposure to sunlight or tanning beds. Promethazine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of promethazine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe drowsiness, weak or shallow breathing;
  • a light-headed feeling, like you might pass out;
  • confusion, agitation, hallucinations, nightmares;
  • seizure (convulsions);
  • fast or slow heartbeats;
  • jaundice (yellowing of the skin or eyes);
  • uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
  • easy bruising or bleeding (nosebleeds, bleeding gums);
  • sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing; or
  • severe nervous system reaction --very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.

Common side effects may include:

  • drowsiness, dizziness;
  • ringing in your ears;
  • double vision;
  • feeling nervous;
  • dry mouth; or
  • tiredness, sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect promethazine?

Using promethazine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect promethazine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your doctor or pharmacist can provide more information about promethazine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.